http://hdl.handle.net/11434/160 2026-07-10T23:36:52Z http://hdl.handle.net/11434/2429 Title: Guideline of guidelines: pelvic lymph node dissection at time of radical prostatectomy. Epworth Authors: Carll, Jonathon; Lawrentschuk, Nathan Abstract: Objective: To provide a comprehensive review, analysis and critique of guidelines from various oncological and urological organisations regarding the use pelvic lymph node dissection (PLND) in men undergoing radical prostatectomy (RP) for primary treatment of prostate cancer (PCa). Methods: PubMed, Google Scholar and the official webpages of major urological and oncological societies were searched for PCa guidelines. Guidelines were assessed for recommendations and opinions regarding the use of PLND. A total of 15 guidelines were identified and included for this review. Results: There is consensus amongst guidelines that an extended template (ePLND), is the preferred templated when PLND is to be undertaken. The majority of guidelines acknowledge the lack of proven oncological benefit from PLND, and that the largest benefit is from improved staging information. However, there is significant divergence between the guidelines about which patients should undergo PLND. Some guidelines advocate for the abandonment of PLND altogether, whilst others adopt a risk-stratified approach, suggesting that patients should be offered PLND based on nomograms or clinical risk stratification. Conclusion: Whilst ePLND is recommended by some guidelines for select patients undergoing RP, it remains a contentious topic with significant discordance between guidelines regarding patient selection. Given the lack of proven oncological benefit and significant morbidity from the procedure, careful selection is required. It is uncertain as to how pathological findings on PLND will change management given recent trends towards salvage rather than adjuvant radiotherapy, and improved preoperative staging with prostate-specific membrane antigen-positron emission tomography/computed tomography. 2026-04-01T00:00:00Z http://hdl.handle.net/11434/2364 Title: A prospective cohort study of men receiving irreversible electroporation (NanoKnife) for prostate cancer. Epworth Authors: Carll, Jonathon; Lawrentschuk, Nathan; Chengodu, Thili Abstract: Irreversible Electroporation (IRE) also known as Nanoknife, is an emerging focal therapy used in the treatment of localised prostate cancer. It remains an investigational, technique with long-term oncological outcomes not yet well-established. This study assesses the initial experience from a prospectively collected database at a single institution. 2025-08-01T00:00:00Z http://hdl.handle.net/11434/2122 Title: Sclerosing perivascular epithelioid cell tumour (PEComa) of the testis in a patient with tuberous sclerosis complex. Epworth Authors: Chee, Justin Abstract: Description of a case of sclerosing perivascular epitheloid cell tumour (PEComa) of the testis. 2022-05-01T00:00:00Z http://hdl.handle.net/11434/2099 Title: PSMA PET-CT funding grants free access to superior staging for Australian men with prostate cancer. Epworth Authors: Moon, Daniel; Murphy, Declan; Lawrentschuk, Nathan 2022-05-01T00:00:00Z