http://hdl.handle.net/11434/7 Sat, 18 Apr 2026 03:59:00 GMT 2026-04-18T03:59:00Z http://hdl.handle.net/11434/2324 Title: The role of indocyanine green with near infrared imaging for the intraoperative detection and enhancement of endometriosis lesions: A narrative review. Epworth Authors: Tarana, Lucky; Kathurusinghe, Shamitha; Rajasinghe, Minoli Abstract: Background: There is a clinical need for improved intraoperative detection of endometriosis, and the use of Indocyanine Green with Near-Infrared Imaging (NIR-ICG) is a novel technique for this purpose. The aim of this review is to determine whether NIR-ICG is an effective tool for endometriosis detection and establish an evidence-based methodology for its use. Methods: This review searches Ovid MEDLINE and Embase through July 2023 and considers primary literature published in English describing the use of NIR-ICG to detect endometriosis intraoperatively. Case studies, video demonstrations and articles describing NIR-ICG used for other surgical roles were not considered. Identified studies were screened independently by two authors, and data was extracted by a single author. Results: NIR-ICG was found to enhance the detection of endometriosis in six out of the nine included studies with additional lesion identification, and to have an unchanged or reduced efficacy compared to current standards in the remaining three. Across all studies there were lesions missed by NIR-ICG which were detected by conventional imaging. A greater duration of time between dye administration and visualisation of lesions was found to be more effective for detection. The ideal ICG protocol proposed from this review is a fixed amount of dye proportional to patient weight prior to surgery (0.25-0.3 mg/kg) followed by a longer waiting time before imaging (10-30 min). Conclusion: NIR-ICG has a possible role to enhance the identification of endometriosis intraoperatively as an adjunct to conventional white light imaging, particularly deeper infiltrating disease. However, substantial further research is required in this field. Sun, 01 Sep 2024 00:00:00 GMT http://hdl.handle.net/11434/2324 2024-09-01T00:00:00Z http://hdl.handle.net/11434/2184 Title: Lateral lumbar interbody fusion using expandable vs static titanium interbody cages: a prospective cohort study of clinical and radiographic outcomes. Epworth Authors: Malham, Gregory; Biddau, Dean; Wang, Yi Yuen Abstract: Background: Expandable cages are a recent development employed to reduce subsidence and improve fusion compared with static cages as they alleviate the need for repeated trialing or overdistraction of the disc space. This study aimed to compare the radiographic and clinical outcomes in patients undergoing lateral lumbar interbody fusion (LLIF) with either an expandable or static titanium cage. Methods: This was a prospective study of 98 consecutive patients undergoing LLIF performed over a 2-year period, with the first 50 patients receiving static cages and the following 48 receiving expandable cages. Radiographic evaluation included interbody fusion status, cage subsidence, and change in segmental lordosis and disc height. Clinical evaluation assessed patient-reported outcome measures (PROMs), including the Oswestry Disability Index, visual analog scale (VAS) for back and leg pain, and short form-12 physical and mental health survey scores collected at 3, 6, and 12 months postoperatively. Results: The 98 patients had 169 cages impacted (84 expandable vs 85 static). Mean age was 69.2 years, and 53.1% were women. There was no significant difference between the 2 groups in terms of age, gender, body mass index, or smoking status. The expandable cage group had higher rates of interbody fusion (94.0% vs 82.9%, P = 0.039) at 12 months as well as significantly reduced implant subsidence rates at all follow-up timepoints (4% vs 18% at 3 months; 4% vs 20% at 6 and 12 months). Patients from the expandable cage group showed a mean 1.9 more points of reduction in VAS back pain (P = 0.006) and 2.49 points greater reduction in VAS leg pain (P = 0.023) at 12-month follow-up. Conclusions: Expandable lateral interbody spacers resulted in significantly improved fusion rates with reduced subsidence risks and statistically significant improvement in PROMs up to 12 months postoperatively compared with impacted lateral static cages. Clinical relevance: The data provide clinical relevance in favoring expandable cages over static cages for enhanced fusion outcomes in lumbar fusions. Sat, 01 Apr 2023 00:00:00 GMT http://hdl.handle.net/11434/2184 2023-04-01T00:00:00Z http://hdl.handle.net/11434/1718 Title: MP36-19 What is the accuracy of 68 GA-PSMA PET/CT in detecting primary prostate cancers compared to multiparametric MRI? Epworth Authors: Moon, Daniel; Grummet, Jeremy; Frydenberg, Mark; Landau, Adam Abstract: PSMA PET/CT has demonstrated superior sensitivity in detecting prostate cancer metastases compared to traditional staging modalities and seen a high degree of utilisation in the Australian setting. However, there is little data published on the role of PSMA PET/CT in detecting and diagnosing primary prostate cancer. We compared the accuracy of PSMA PET/CT to multiparametric MRI for the detection of clinically significant primary prostate cancer. A local prospective database (REDCap-Monash) was maintained on patients who underwent MRI in our group urology practice from July 2013 to December 2017. All patients who had an MRI for diagnosis of prostate cancer, subsequent transperineal biopsy, and a PSMA PET/CT for initial staging were included, with significant cancer being defined as greater than or equal to Gleason 3+4=7 (ISUP Grade Group 2). The database contained 2,283 patients who underwent prostate MRI. 239 patients subsequently underwent both biopsy and PSMA PET/CT. 202 biopsies (84.5%) showed significant cancer. Of the non-significant cancer cases, 21 (8.8%) revealed Grade Group 1 lesions and 16 (6.7%) were benign. For significant cancers, 189 PSMA PET/CT scans demonstrated local PSMA avidity in the prostate, compared to 174 positive (PIRADS 4 or 5) MRI scans. Description: Includes one table outlining research results Mon, 01 Apr 2019 00:00:00 GMT http://hdl.handle.net/11434/1718 2019-04-01T00:00:00Z http://hdl.handle.net/11434/1543 Title: CT-guided nephrostomy: Re-inventing the wheel for the occasional interventionalist. Epworth Authors: Smith, Paul; Luong, Henry Abstract: Percutaneous nephrostomy insertion has, in recent times, become a subspecialised skill performed by an interventional trained Radiologist. However, this creates access issues, particularly in remote and regional medical centres. In this article, we describe a simple and effective method for computed tomography (CT)-guided percutaneous nephrostomy insertion, utilising the CT interventional skills of the general radiologist. Wed, 01 Aug 2018 00:00:00 GMT http://hdl.handle.net/11434/1543 2018-08-01T00:00:00Z