Antipsychotic use for agitation after traumatic brain injury.

Abstract

• Determine the frequency and type of antipsychotics used for agitation during PTA • To examine the relationship between antipsychotic use and agitation levels • To provide observational data on the efficacy of antipsychotic use in reducing agitation in PTAAtypical antipsychotics were frequently used to treat agitation during PTA even in cases with mild or subclinical agitation • Uncontrolled observational data found no evidence that agitation scores reduced after starting or increasing antipsychotics • Strong need for controlled studies to examine efficacy of antipsychotics for agitation during PTA • Recommend using agitation measure such as ABS to monitor effectiveness of medication interventions