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Please use this identifier to cite or link to this item: http://hdl.handle.net/11434/2038
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dc.contributor.authorPrince, Miles-
dc.contributor.otherCampbell, Belinda-
dc.contributor.otherHofman, Michael-
dc.date.accessioned2021-11-22T02:38:22Z-
dc.date.available2021-11-22T02:38:22Z-
dc.date.issued2020-11-
dc.identifier.citationClin Nucl Med. 2019 Nov;44(11):e624-e626.en_US
dc.identifier.issn03639762en_US
dc.identifier.issn15360229en_US
dc.identifier.urihttp://hdl.handle.net/11434/2038-
dc.description.abstractF-Fluorothymidine-positron emission tomography with CT fusion ([F]FLT-PET/CT) offers a unique and non-invasive method for three-dimensional localization and quantification of functional bone marrow. [F]FLT-PET/CT has potential application in radiotherapy planning when risk of marrow toxicity is a significant clinical concern. In this patient with chemo-refractory, transformed lymphoma and treatment-induced cytopenias, [F]FLT-PET/CT was a novel and useful adjunct to (1) image the distribution of functional bone marrow reserve, (2) guide "marrow-sparing" radiotherapy planning, and (3) quantify the effects of radiotherapy-induced bone marrow suppression both in-field and out-of-field.en_US
dc.publisherLippincott Williams and Wilkins Ltd.en_US
dc.subject[18F]Fluorothymidine-PET ([18F]FLT-PET)en_US
dc.subjectRegional Bone Marrow Functionen_US
dc.subjectTreatment-Induced Cytopeniasen_US
dc.subjectMarrow-Sparing Radiotherapyen_US
dc.subjectF-Fluorothymidine-Positron Emission Tomographyen_US
dc.subjectCT Fusionen_US
dc.subjectThree-Dimensional Localizationen_US
dc.subjectQuantification of Functional Bone Marrowen_US
dc.subjectMarrow Toxicityen_US
dc.subjectChemo-Refractoryen_US
dc.subjectTransformed Lymphomaen_US
dc.subjectTreatment-Induced Cytopeniasen_US
dc.subjectBone Marrow Reserveen_US
dc.subjectRadiotherapy-Induced Bone Marrow Suppressionen_US
dc.subjectEpworth Centre for Immunotherapies and Snowdome Laboratoriesen_US
dc.subjectMolecular Oncology and Cancer Immunologyen_US
dc.subjectCancer Services Clinical Institute, Epworth HealthCare, Victoria, Australiaen_US
dc.titleA novel application of [18F] fluorothymidine-PET ([18F]FLT-PET) in clinical practice to quantify regional bone marrow function in a patient with treatment-Induced cytopenias and to guide "marrow-sparing" radiotherapy.en_US
dc.typeJournal Articleen_US
dc.identifier.doi10.1097/RLU.0000000000002785en_US
dc.identifier.journaltitleClinical Nuclear Medicineen_US
dc.description.pubmedurihttps://pubmed.ncbi.nlm.nih.gov/31584492en_US
dc.description.affiliatesCentre of Molecular Imaging, Peter MacCallum Cancer Centre, Melbourne, Victoria.en_US
dc.description.affiliatesSir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.en_US
dc.type.studyortrialClinical Trialen_US
dc.type.contenttypeTexten_US
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