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http://hdl.handle.net/11434/2151| Title: | Investigating uterine natural killer cells through next generation sequencing - A pilot gene expression study. |
| Epworth Authors: | Teh, Wan |
| Other Authors: | Rogers, Peter |
| Keywords: | Uterine Natural Killer Cells uNK Next Generation Sequencing NGS Molecular Study Molecular Markers Human Reproduction Protein Coding Genes Genes Immune Related Functions Women’s and Children’s Clinical Institute, Epworth HealthCare, Melbourne, Australia |
| Issue Date: | Oct-2022 |
| Conference Name: | Epworth HealthCare Research Month 2022 |
| Conference Location: | Epworth Research Institute, Victoria, Australia |
| Abstract: | Uterine natural killer (uNK) cells form the major leucocyte population in the stroma in the late secretory phase endometrium. Their actual function is unknown with available data suggesting potential role in angiogenesis regulation, decidualization and placentation. Next generation sequencing (NGS) can be used to accurately define day of menstrual cycle through endometrial gene expression. Genes uniquely expressed by uNK are currently unknown. However, previous studies of first trimester decidua and blood have identified genes that are uniquely expressed by these NK cells (1-3). Aim for this study: To identify potential molecular markers of uNK cells. |
| URI: | http://hdl.handle.net/11434/2151 |
| Type: | Conference Poster |
| Affiliated Organisations: | Reproductive Services, Royal Women’s Hospital, Parkville 3052; Melbourne IVF, East Melbourne 3002 Department of Obstetrics and Gynaecology, University of Melbourne, Royal Women’s Hospital, Parkville 3052, Victoria, Australia |
| Type of Clinical Study or Trial: | Descriptive Study |
| Appears in Collections: | Research Week |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Teh WT Investigating Uterine Natural Killer Cells Through Next Generation Sequencing.pdf | 2.69 MB | Adobe PDF |  View/Open |
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