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Title: Malignant transformation of Intraductal Papillary Mucinous Neoplasm (IPMN): a multi-centre retrospective analysis from the IPMN registry.
Epworth Authors: Metz, Andrew
Fox, Adrian
Other Authors: Meehan, Edward
Lin, Lyman
Bradshaw, Luke
Chong, Lyn
Croagh, Daniel
Huynh, Isabelle
Ji, Katharine
Knowles, Brett
Lim, Eunice
Panuganti, Vishwakar
Santucci, Jordan
Schneider, Daniel
Sutherland, Tom
Wong, Enoch
Xu, Ruiwen
Keywords: Intraductal Papillary Mucinous Neoplasm
Pancreatic Ductal Adenocarcinoma
Fukuoka Consensus
Endoscopic Ultrasound
Cancer Services Clinical Institute, Epworth HealthCare, Victoria, Australia
Issue Date: Oct-2023
Conference Name: Epworth HealthCare Research Month 2023
Conference Location: Epworth Research Institute, Victoria, Australia
Abstract: Introduction: Pancreatic ductal adenocarcinoma (PDAC) is predicted to become the second most lethal cancer in Australia by 2030 and early detection of the cancer is crucial for timely surgical intervention [1]. Intraductal Papillary Mucinous Neoplasms (IPMN) are the most common radiological detectable precursor lesion to PDAC. Data from international cohorts demonstrates different malignant potentials for main duct and branch duct IPMNs. Multiple surveillance guidelines for IPMN have been proposed but there are still gaps in our knowledge of the natural history of these neoplasms. Conclusions: Classification of IPMN based on Fukuoka consensus correlates with the incidence of PDAC. The majority of those with or developing high-risk stigmata are not undergoing surgery. To further investigate the validity of the Fukuoka Consensus on the surveillance and treatment of IPMN, a prospective arm with a larger sample size, a more extended follow-up period and data on the clinical management of these patients is underway.
Type: Conference Poster
Affiliated Organisations: Monash Health, Victoria, Australia
St Vincent's Health, Victoria, Australia
Eastern Health, Victoria, Australia
Melbourne Health, Victoria, Australia
Type of Clinical Study or Trial: Retrospective studies
Appears in Collections:Research Month

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