Please use this identifier to cite or link to this item: http://hdl.handle.net/11434/2143
Title: Amyloid-β and tau imaging in chronic traumatic brain injury: a cross-sectional study.
Epworth Authors: Ponsford, Jennie
Spitz, Gershon
Roberts, Caroline
Other Authors: Hicks, Amelia
Dore, Vincent
Krishnadas, Natasha
Rowe, Christopher
Keywords: Amyloid-β and Tau
Traumatic Brain Injury
TBI
PET Imaging
Alzheimer’s Disease
Monash Epworth Rehabilitation Research Centre, Epworth Healthcare, Richmond, Victoria, Australia
Rehabilitation, Mental Health and Chronic Pain Clinical Institute, Epworth HealthCare, Victoria, Australia.
Issue Date: Oct-2022
Conference Name: Epworth HealthCare Research Month 2022
Conference Location: Epworth Research Institute, Victoria, Australia
Abstract: Aims: 1.to assess amyloid-β and tau burden in long-term TBI survivors and healthy controls using PET imaging. 2. to examine PET data in relation to time since injury and age at injury. TBI has been increasingly promoted as a risk factor for Alzheimer’s disease. Evidence of amyloid-β and tau beyond the initial years post injury is inconclusive. There is conflicting evidence from PET, CSF and post-mortem studies of elevated amyloid-β and tau pathology in chronic TBI survivors compared to controls. The relationships between amyloid-β and tau pathology and injury characteristics, such as time since injury and age at injury, are also unclear.
URI: http://hdl.handle.net/11434/2143
Type: Conference Poster
Affiliated Organisations: Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Australia.
Department of Molecular Imaging and Therapy, Austin Health, Australia
Florey Department of Neuroscience and Mental Health, University of Melbourne, Australia
CSIRO Health and Biosecurity Flagship, The Australian e-Health Research Centre, Australia
Type of Clinical Study or Trial: Cross-Sectional Study
Appears in Collections:Research Week

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